Human model systems are miniature human tissues and organs derived from human stem cells that more accurately model human biology than animals. In addition to avoiding cruel animal experiments, human model systems can result in advancements in human health and disease research.

In a huge acknowledgement that we need to move away from animal
research, Swiss company Roche, the fifth-largest pharmaceutical
company in the world, has just launched an Institute for Human
Biology to focus on human model systems that more precisely simulate
human disease than animal experiments.
Roche’s research and early development head Dr. Hans Clevers states
that “Human model systems such as organoids are the future of our
industry. They have the potential to enhance almost all the steps
involved in the research and development of innovative medicine.”
We report on two other perfect examples of such human models:
Researchers have developed a sophisticated vein on a chip to study
blood clotting mechanisms, while another group of scientists are
using human colorectal tumor cells to grow organoid “avatars” for
testing treatments, delivering more accurate results than those
developed in mouse models.

All of this begs the question: Why are we still testing on animals?
The answer lies in the huge power and influence of the animal
experimentation industry, which CAARE is working daily to oppose.
The pharmaceutical company Roche has launched a new institute in
Switzerland called the Institute of Human Biology (IHB). The
institute will include scientists and bioengineers from both
academia and the pharmaceutical industry and will be focused on
accelerating research and development into human model systems like
organoids.
Human model systems are miniature human tissues and organs derived
from human stem cells that more accurately model human biology than
animals. In addition to avoiding cruel animal experiments, human
model systems can result in advancements in human health and disease
research.